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Morphometric analysis and sexual dimorphism of corpus callosum: A MRI Study

Abstract

Rajan Bhatnagar

The aim of the present study was to measure the various dimensions of the Corpus Callosum (CC) in normal adult Indian men and women and to identify gender related differences, if any. Corpus Callosum (CC) is the major anatomical and functional commissure linking the two cerebral hemispheres. It connects cortical as well as subcortical region of the right and left sides of the brain and plays an essential role in the integration of information between the two hemispheres. Variations in size and morphology of Corpus Callosum are elucidated in a wide range of neuropsychiatric disorders [1-5]. Study of difference in shape and size of Corpus Callosum and its subjective association with intelligence and apprehensive ability has engrossed our scientists. Literature hints towards a possible relation between different morphometry of Corpus Callosum with the difference in cognitivity and behavioural pattern seen in males and females. Hence sexual dimorphism of Corpus Callosum is a matter of increasing research. Our study sample comprised 200 subjects (109males and 91 females) who were referred to Dr. Ram Manohar Lohia Institute of Medical Sciences for head MRIs and were reported to have normal images by the Radiologist

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