Bioinformatic approaches to assess the genetic basis of Neurological Disease

Abstract

Shahid Mian

Neurological disorders include a good spectrum of diseases within the central systema nervosum (CNS). Up till now, many neurological disorders are classified, with symptoms varying from cognitive dysfunction to manic behavior or depression. thanks to the complex nature of this group of diseases, it's difficult to spot the mechanisms using conventional methodologies, where only small pathways around specific target genes are investigated. the arrival of systems biology approaches has made it possible to review these complex problems from the whole-genome perspective. Within the recent years, genomic technologies are increasingly applied to the investigation of neurological disorders.

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