GJMPR Navigation
Publication Ethics
Call For Paper
Editorial Board
Guide to Authors
Editorial Workflow
Submit Manuscript
Viewing Options
[View Abstract]
[View Full Text PDF]
[Download Full Text PDF]
Authors Articles on Google Scholar
Kagimura Quinteiro Matti
Authors Articles on Pubmed
Kagimura Quinteiro Matti
Email this Article to a friend
Print this Article
Viewed: 149
Forwarded: 0
Printed: 65
Downloaded: 106
Browse Journals By Category
Agricultural Sciences
Biological Sciences
Legal Studies
Medical Sciences
Physical Sciences
Social Sciences

Newsletters Subscription

Global Journal of Medicinal Plants Research

ISSN: 0274-3248 Vol. 2 (10), pp. 253-258, October, 2016.                                                              


Full Length Research Paper


Antifungal effect of the aqueous extract of leaves of S. cayennensis collected in the Southwest region of Paraná, Brazil


 Kagimura Quinteiro Mattiello


Accepted 10 September, 2016

The objective of this study was to evaluate the antifungal activity of the aqueous extract of the leaves of the "verbena" (gervão roxo) Stachytarpheta cayennensis, (Rich.) Vahl. (Verbenaceae), by determining the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) on different species and strains of the genus Candida. In this study, the species Candida albicans, Candida tropicalis, Candida glabrata, Candida stellatoidea, Candida dubliniensis and Candida krusei were included. Four strains of C. albicans and three of C. tropicalis were used, while for the other species only one strain was tested. These yeasts were used in this study because of their importance and frequency in the oral cavity. The yeasts were subjected to treatments with concentrations of the aqueous extract ranging from 0.09 to 25 mg mL-1. The results indicated, however, that concentrations of less than 12.5 mg mL-1 were insufficient to show a fungistatic or fungicidal effect. The concentration of 12.5 mg mL-1 showed a fungistatic effect on most tested strains and species, C. albicans CαFB-12 and ATCC-44858; C. tropicalis CTFB-22 and CTFB29. The fungicidal effect (MFC) was observed only on the species C. krusei for the concentration of 12.5 mg mL-1. Based on the employed methodology, it is concluded that the aqueous extract of S. cayennensis showed an antifungal, mainly fungistatic, effect on oral Candida species.

Key words: Yeasts, candidiasis, metabolites, Stachytarpheta cayennensis.